Difficulty annotation: 1 - 3, where 3 = most difficult
2023-08-03
Step count: 12 | Difficulty: 2
A divergent approach to the synthesis of the yohimbinoid alkaloids venenatine and alstovenine
Lebold, T. P.; Wood, J. L.; Deitch, J.; Lodewyk, M. W.; Tantillo, D. J.; Sarpong, R. Nat. Chem. 2013, 5, 126–131. DOI: 10.1038/nchem.1528.
[Problem PDF] | [Key PDF] | [Mechanisms PDF]
2023-07-20
Step count: 16 | Difficulty: 2
Total Synthesis of (−)-5-Deoxyenterocin and Attempted Late-Stage Functionalization Reactions
Koser, L.; Bach, T. Chem. Eur. J. 2023, e202301996. DOI: 10.1002/chem.20230199